Clearness vs. Cleverness
An important message to keep in mind at all times is to make sure that in your presentation your message is absolutely and unmistakably clear. This above all else should be the focus of your efforts when creating your presentation. You can worry about how “cleverly” you use your visuals etc after that. Although it is nice to have people comment on the amazing transitions you used, at the end of the day you want them to remember the “meat” of the presentation.
So, once you have crafted a clear message it is then up to you to ensure that any “cleverness” you do end up using does not end up interfering with the message. For example, using a distracting array of transitions between slides, might distract from what the slides were trying to communicate. A font that might indeed be cool and… “unique” (it’s probably unique for a reason!), might also distract from the clarity of a slide and so too might using every text animation effect that Powerpoint provides you with.
Remember, in order to ensure that your message gets across and is understood always choose Clearness over Cleverness.